Nifoxipam Pellets

Nifoxipam Pellets

$25.00$425.00

Rating:
Shipping:
€10 (flat rate)
Ship From:
Netherlands, Germany, Sweden, France, UK
Compare

Description

buy Nifoxipam Pellets online europe

Product Description.buy Nifoxipam Pellets online europe

Nifoxipam (3-hydroxydesmethylflunitrazepam, DP 370) is a benzodiazepine that is a minor metabolite of flunitrazepam. Nifoxipam produces strong tranquilizing and sleep-prolonging effects.buy Nifoxipam Pellets online europe

Nifoxipam pellets contain 2mg Nifoxipam

Product Name: 2mg Nifoxipam Pellets
Cas No: 74723-10-7
Formula: C15H10FN3O4
IUPAC: 5-(2-fluorophenyl)-3-hydroxy-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
Appearance:
Purity:

Pharmacology

Nifoxipam produces strong tranquillising and sleep-prolonging effects and has much lower toxicity compared to lormetazepam and flunitrazepam in mice.

As with other benzodiazepines, nifoxipam binds to specific sites on the GABAA receptor, and is in the same class of hypnotic nitrobenzodiazepines as nitrazepam, nimetazepam, flunitrazepam, and flurazepam. As with all GABAergic drugs, overdose can be lethal when mixed with other depressants such as opioids and alcohol. This is particularly concerning because Nifoxipam is a research chemical and has not been approved for medicinal use.

Usage of Nifoxipam on a regular basis can cause typical benzodiazepine addiction, habituation, and tolerance.buy Nifoxipam Pellets online europe

Benzodiazepines produce a variety of effects by binding to the benzodiazepine receptor site and magnifying the efficiency and effects of the neurotransmitter gamma aminobutyric acid (GABA) by acting on its receptors.As this site is the most prolific inhibitory receptor set within the brain, its modulation results in the sedating (or calming effects) of nifoxipam on the nervous system. The anticonvulsant properties of benzodiazepines may be, in part or entirely, due to binding to voltage-dependent sodium channels rather than benzodiazepine receptors.

Chemistry

Nifoxipam is a drug of the benzodiazepine class. Benzodiazepine drugs contain a benzene ring fused to a diazepine ring, which is a seven membered ring with the two nitrogen constituents located at R1 and R4. Nifoxipam, or 3-hydroxydesmethylflunitrazepam, is an active metabolite of flunitrazepam.[7] The benzyl ring of nifoxipam is substituted at R7 with a nitro group, NO2-. AR2flourine substituted phenyl ring is bound to this structure at R5. Additionally, nifoxipam contains a hydroxy (OH-) group substituted at R3. Nifoxipam also contains an oxygen group double bonded to R2 of its diazepine ring to form a ketone. This oxygen substitution at R2 is shared with benzodiazepine drugs with the suffix -azepam.

As with flunitrazepam, nifoxipam is likely insoluble in water, although the addition of a hydroxyl group may increase water solubility.

Nifoxipam has a molecular weight of 315.26 g/mol.

 

Additional information

QUANTITY

50, 100, 250, 500, 1000

Reviews

There are no reviews yet.

Be the first to review “Nifoxipam Pellets”

Your email address will not be published.